The average age at diagnosis with OC in FC variant carriers (average=58; median=60 years) is comparable to that of AUS variant carriers as well as Pan-Cancer – TCGA variant carriers (average=59; median=59 years), which in turn is comparable with that of carriers of BRCA2 PVs (average=58 years) (41) and the general population (median=63 years) (112, 113). The gene discussed is BRCA2; the disease is polyarteritis nodosa.