In previous studies we have also demonstrated complete or partial loss of wild-type alleles in tumour DNA from FC carriers of RAD51C c.705G>T; p.Lys235Asn (43), RAD51D c.620C>T; p.Ser207Leu (43, 44) and FANCI c.1813C>T; p.Leu605Phe (24) also from the analyses of RRCancer biobank materials. This evidence concerns the gene FANCI and neoplasm.