Analyses of the GEO and TCGA databases revealed the upregulation of THBS2 in GC tumor tissues relative to normal paracancerous tissues (TCGA: P<0.01; GSE66229: P=0.003; GSE54129: P<0.0001; GSE27342: P<0.0001; Figures 7A–C, E). This evidence concerns the gene THBS2 and neoplasm.