Specifically, the risk score model for predicting CRC prognosis based on 6 CRLs is shown as follows: risk score = expression value of AC009315.1 ∗ 0.15835365544805 + expression value of PLS3-AS1 ∗ 0.100587632623172 + expression value of ZEB1-AS1 ∗ 0.0274302502732273 + expression value of AC007608.3 ∗ 0.0549982300165668 + expression value of AC010789.2 ∗ 0.166645095217608 + expression value of AC010207.1 ∗ 0.403357464363707. Here, ZEB1 is linked to colorectal carcinoma.