To be specific, STAT1 and STAT4 were manifested as risk factors of KIRP with HR > 1, as well as STAT2 and STAT4 of KIRC, while STAT4 and STAT5B were revealed to be protective factors of PAAD with HR < 1, as well as STAT6 of BLCA and SARC. Here, STAT5B is linked to bladder transitional cell carcinoma.