In the tumor environment, Figures 6A,B show that samples in the high ERPI group had higher B cell, CD8+ T cell, macrophage cell, NK T cell, and CD4+ Th1/2 cell infiltration, while samples in the low ERPI group had higher endothelial cell infiltration in both the TCGA training and TCGA test groups. The gene discussed is CD8A; the disease is neoplasm.