Electroacupuncture elevates ghrelin levels in the hypothalamus, stomach antrum, and small intestine and promotes adenosine 5′-monophosphate-activated protein kinase (AMPK)/Tuberous Sclerosis Complex 2 (TSC2)/Ras homolog enriched in brain (Rheb) signaling by inhibiting mTOR, resulting in dyspepsia relief (Tang et al., 2020). Here, TSC2 is linked to dyspepsia.