Further interrogation of The Cancer Genome Atlas (TCGA) PanCancer breast cancer cohort, which contains clinical information on more than 1,000 patients with breast cancer, showed WAVE2 mRNA expression levels to be significantly (P < 0.01) higher in the basal (TNBC) breast cancer subtype, as compared with their Her2+ and luminal counterparts or to normal breast tissue (Fig. 1C; Supplementary Fig. S1A and S1B). This evidence concerns the gene ERBB2 and breast cancer.