Muscle laminopathies may associate cardiac disease at any age and range from congenital muscular dystrophy (LMNA-related congenital muscular dystrophy, or L-CMD) to late-onset manifestations (limb–girdle muscular dystrophy 1B, or LGMD1B; and autosomal-dominant EDMD). The gene discussed is LMNA; the disease is congenital muscular dystrophy.