10 hub genes were found in the dataset between the MDS patient group and healthy controls, where BLNK, SOCS2, SIK1, RGS1, STK17B, MEF2C, and PDE4B showed a downregulation trend in MDS, however, PIM1, RRAS, and PTPN6 showed opposite changes (Figures 5A–J). Here, SIK1 is linked to myelodysplastic syndrome.