However, our study found high concentrations of IL-1β in saliva (p = 0.057) from G2 (P) and G4 (P-OSA) compared to G1 (H) and found that 80% of patients of both groups had the highest concentration of IL-1β (40–60 pg/mL), a determinant cytokine in periodontitis. The gene discussed is IL1B; the disease is obstructive sleep apnea syndrome.