APIP, DDX3X, DHX9, and TNFRSF21 were significantly downregulated in the T2D group, whereas CASP1, GBP2, GSDMB, GSDMD, NLRP1, NOD2, PYCARD, TREM2, and ZBP1 were significantly upregulated in the T2D group. Here, GBP2 is linked to type 2 diabetes mellitus.