Existing studies have identified that several laboratory parameters are independent predictors of GDM, such as glycemic markers (e.g., fasting glucose and HBA1c levels), alanine aminotransferase (ALT) levels, and thyroid function (levels of the thyroid hormones T3 and T4) (9, 18, 20); all of these are available clinically in the first trimester of pregnancy. The gene discussed is GPT; the disease is gestational diabetes.