CNP and frontotemporal dementia: In parietal white matter, PLP (F = 14.64, p < 0.0001) was significantly reduced in FTD-GRN compared to both control and FTD-C9orf72 cases, whereas CNP (F = 0.88, p = 0.43) and MBP (F = 1.02, p = 0.38) were unchanged across the three sample groups (Fig. 4C-D).