We observed that TERRA levels increased after hit 17 treatments in a dose-dependent manner with remarkable fold change at the dose of 5 μM ranging from 2- to 10-fold in MM cell lines (Fig. 2A-D) and at the dose 20 μM in the range of 2- to 20-fold in ALT cell lines (Fig. S2A-C). The gene discussed is GPT; the disease is Miyoshi myopathy.