Next, in serendipitous response to a recent call for further study (Yan, 2021), we here report signs of sex differences in this experimental model of AKI, with females expressing much higher renal injury markers in comparison to males, and corresponding AKI‐dependent effects on PTH and FGF23 were visible in females only but less so in males. The gene discussed is FGF23; the disease is acute kidney injury.