Here, we set out to describe the role of FGFR modulator Memo1 in the osteoblast and in bone‐derived FGF23 expression under experimental AKI, based on reports that FGFR‐Klotho signaling is required for FGF23 expression during chronic kidney disease in mice (Kaludjerovic et al., 2017). The gene discussed is KL; the disease is acute kidney injury.