In contrast, both decreasing renal clearance and an increase of cytokines such as TNF and TGFβ, might be the link between AKI and the excessive Fgf23 expression in different lymphoid and parenchymatous organs contributing high circulating FGF23 levels (Egli‐spichtig et al., 2018). The gene discussed is FGF23; the disease is acute kidney injury.