Further ROC curve analysis showed that the AUC of NSE and SCC levels for predicting tumor recurrence and metastasis in Lung cancer radiotherapy patients was 0.848 and 0.755, the critical value was 21.98 ng/mL and 1.59 ng/mL, the sensitivity was 92.86% and 82.14%, and the specificity was 71.87% and 62.96%, respectively. Here, ENO2 is linked to neoplasm.