SERPINB3 and neoplasm: Squamous Cell Carcinoma Antigen (SCC) was originally extracted from cervical squamous cell carcinoma in 1977 and is a sub-fragment of tumor-associated antigen TA-4, widely presenting in the cytoplasm of squamous cell carcinomas of the uterus, cervix, lung, head and neck, etc., especially in non-keratinizing carcinoma cells, the content is more abundant.6