HSP90 is involved in cancer-related signaling pathways such as HER-2, MET, BRAF, EGFR, STAT3, KRAS, PI3-K, c-Raf, p23, p53, FAK, TNFR-1 and Toll-like receptors (Burrows et al. 2004; Moser et al. 2009; Banz et al. 2009; Chatterjee and Burns 2017; Calderwood 2018; Boroumand et al. 2018; Kataria et al. 2019; Albakova and Mangasarova 2021). This evidence concerns the gene ERBB2 and cancer.