RAF1 and colorectal cancer: In colorectal cancer KRAS (including Raf/Ras/MEK/Erk), EGFR, c-Met, Apo2L, FAK, NF-κB are plausible molecule targets (Moser et al. 2009; Therkildsen et al. 2014; Alwers et al. 2019; Henderson et al. 2019; Reynolds et al. 2019; Levin-Sparenberg et al. 2020; Afolabi et al. 2022).