The results revealed that serum CRP level in CHF patients was negatively correlated with LVEF and FS (r =  − 0.789, P < 0.001; r =  − 0.665, P < 0.001) (Fig. 2A/B), whereas positively correlated with E/A (r = 0.725, P < 0.001) (Fig. 2C). Here, CRP is linked to congestive heart failure.