BMP4 and cardiovascular disorder: The 4 autosomal DNAm sites were mapped to 3 genes, including cg01911745 on ADCYAP1R1, which has been related to post-traumatic stress disorder, accommodative spasm, and childhood asthma [33]; cg01963240 on BMP4, which regulates embryonic development and adipogenesis and may also be involved in the pathology of multiple cardiovascular diseases and human cancers [34]; and cg02927373 on LOC105372441, which encodes a long noncoding RNA.