CRP and major depressive disorder: The results also indicated that a 1-SD decrease in blood NEU1 expression was associated with decreased inflammatory factor levels (CRP) of 0.168 mg/l (95% CI: 0.045–0.290) (eTable 7, Supplementary Tables) and a lower risk of MDD-UKB (OR = 0.966; 95% CI: 0.948–0.985, p = 5.19 × 10−4) (eFig. 1 and eTable 8, Supplementary Tables).