Homozygous mutations in the ADAMTS17 gene are known to cause Weill-Marchesani syndrome-4 (WMS4, OMIM: 613195), which is characterized by microspherophakia, severe myopia, glaucoma, cataract, brachydactyly, joint stiffness, and short stature22–24. This evidence concerns the gene ADAMTS17 and glaucoma secondary to spherophakia/ectopia lentis and megalocornea.