Since rs2054564 was located in intron 7 of the ADAMTS17 gene and we identified this SNP by focusing on the lumbar DSN among several features of spondylosis, we investigated the potential role of ADAMTS17 in IVDs based on the hypotheses that this SNP may have an impact on ADAMTS17 expression or function, and ADAMTS17 may play a crucial role in IVDs. This evidence concerns the gene ADAMTS17 and spondyloarthropathy.