TET1 and neoplasm: Furthermore, Quantitative real-time PCR results demonstrated that TET1 was downregulated in 54.02% of human colorectum tumor tissues, compared with levels in adjacent normal tissues (Fig. 3B, Normal: 0.01357 ± 0.00070 vs. Malignant: 0.00733 ± 0.00046, p < 0.0001).