To further investigate the role of methylation in ZNF334 inactivation in CRC cells, we detected the expression of TET (TET1, TET2, and TET3) in HCoEpiC and CRC cells (HCT116, RKO, SW480, and HT29) by Quantitative real-time PCR. The gene discussed is TET1; the disease is colorectal carcinoma.