Group-wise differential methylation analyses of the three tumor classes showed that differentially methylated probes (DMPs) identified in both SARC DICER1 and PIS DICER1 were mostly hypomethylated (Fig. 4c and Supplementary Table 5) and distributed genome-wide (Fig. 4d and Supplementary Fig. 5f, g), which again highlights a global hypomethylation phenotype for SARC DICER1 and PIS DICER1. This evidence concerns the gene CDIPT and neoplasm.