CD8A and neoplasm: As shown in Fig. 5e and Supplementary Fig. 22, the MHC-I expression in CD8+ DCs was significantly enhanced than that in CD8− DCs after mU@OMVs immunization, demonstrating that mU@OMVs could facilitate the cross-presentation of tumor antigen by MHC class I molecules in resident CD8+ DCs, contributing to subsequent T-cell stimulation.