PIEZO2 and atrial fibrillation: Then, when the Piezo2‐EGFP‐IRES‐Cre mouse was crossed with a Rosa‐tdTomato reporter mouse (Ai9) to perform lineage tracing, we found that the tdTomato+ Piezo2 lineage cells (Piezo2+ cells and their descendants) included some NC/NP cells and most AF cells (Figure 5H), since the EGFP signal was too weak to be reliably detected.[60] These results indicate a potential role of PIEZO2 in AF biomechanics.