Within specific KEGG pathways, the glutamatergic synapse pathway was enriched among genes associated with PFHxS and PFOS; Huntington disease was associated with genes from the PFOS and PFNA models; insulin secretion, gonadotropin-releasing hormone (GnRH) secretion, and high-affinity IgE receptor (FcεRI) signaling was enriched among genes from the PFNA and PFDA models (p < 0.05). The gene discussed is INS; the disease is juvenile Huntington disease.