In the future, more studies are essential to validate the role of FBXL19 in other aspects of pneumonia in animals, such as pyroptosis, and explore FBXL19 upstream mechanism and FOXM1 downstream mechanism, and confirm the role of the FBXL19/FOXM1 axis in other infection/lung injury models and other types of cells and through other injection methods, such as nasal injection, seeking novel targets for the treatment of pneumonia. The gene discussed is FBXL19; the disease is infection.