The biochemical analysis revealed a significant suppression in the expression of cancerous genes (e.g., Bcl2, cyclin E and cyclin D) and higher expression of pro-apoptotic genes (e.g., caspase-3, Bax, P53 and caspase-9) in BC cells treated with CA-Cur-niosomes compared to unfunctionalized Cur-niosomes and the free Cur [154]. Here, TP53 is linked to breast cancer.