LAT and lung cancer: Similarly, Huang et al. used qPCR to assess differences in tRFs expression between lung cancer tissue (LAT) and adjacent normal lung tissue (ANLT) and found that three tRF-1s, tRF-Ser-TGA-010, tRF-Arg-CCT-018, and tRF-Val-CAC-017, had reduced expression in LAT [100].