FOXK1 and colorectal carcinoma: tRF-29-QU7BPN6ISBJO and tRF-27-Q99P9P9NH5N may also be involved in CRC development through cGMP-PKG signaling [90], and Han et al. suggested that tRF3008A affects FOXK1 expression to inhibit Wnt/β-catenin signaling and prevent CRC cell proliferation and metastasis [69] (Fig. 2b).