GOLM1 and neoplasm: However, there have been several studies examining serum GP73 as a tumor marker for HCC with conflicting results, many studies suggest that GP73 is not useful in the diagnosis of HCC, and the serum GP73 level of patients with liver cirrhosis is even higher than that of HCC [12–15].Because of the above controversies, we must make a systematic meta-analysis of the relevant literature on GP73 diagnosing HCC.