Considering that the patients with advanced CAD who underwent coronary artery bypass surgery in these studies were expected to be more commonly characterized by LV diastolic and systolic dysfunction compared to individuals without CAD, the reported associations of epicardial adipose tissue mRNA expression of resistin, RBP4, and adiponectin with CAD in some studies could be attributed at least in part to the association of these adipokines with LV dysfunction [36, 37]. Here, RBP4 is linked to coronary artery disorder.