IFNB1 and acute myeloid leukemia: To corroborate our data in an independent cohort of AML patients, we retrieved normalized TLR3 expression levels of 152 AML patients from The Cancer Genome Atlas (TCGA) public database (Study Cohort 2), confirming a significant correlation between IFNB1 and TLR3 levels (R = 0.3406; p < 0.0001) (Supplemental Fig. 3E).