Strategies such as 1) screening all pregnant women for anemia and bacteriuria, 2) preventive administration of anthelmintic drugs after the first trimester, 3) implementation of universal access to anti-D immunoglobulin for Rh-negative pregnant women, 4) provision of novel inexpensive sickle cell disease point-of-care test kits in the country, and 5) implementation of a total free antenatal care health policy should be discussed due to the country profile and for enhancing neonatal health outcomes. The gene discussed is RHD; the disease is sickle cell disease.