A next-generation TB test, the Fujifilm SILVAMP TB-LAM assay (Japan; henceforth called FujiLAM), also uses urine and offers higher sensitivity compared with AlereLAM for TB detection in adults with HIV across CD4 count strata, as shown in studies on biobanked samples [5, 11–13] and in a first prospective study using fresh urine [14]. This evidence concerns the gene CD4 and tuberculosis.