In this analysis, only three of the original five T cell biomarkers showed any predictive value with all three metrics predicting relapse (CD45RO T cells and the frequencies of CD8 and DPTs) and the increased frequency of CD8 and DPTs predicting both GVHD (of any grade) and ≥ grade 2 GVHD (fig. Here, CD8A is linked to graft versus host disease.