Nicotine increased HIF-1\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\mathrm{a}$$\end{document}a expression in non-small cell lung cancer cells [85]. The gene discussed is HIF1A; the disease is non-small cell lung carcinoma.