Pharmacological targeting of HIF-1\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\mathrm{a}$$\end{document}a may be a promising approach to manage HS as already suggested for psoriasis and other autoimmune disorders [48, 50, 139, 140]. Here, HIF1A is linked to histiocytic sarcoma.