First, the PPM1M univariate Cox regression analysis of OS results suggested that PPM1M was a risk factor in ACC, COAD, GBM, KICH, KIRC, LGG, LIHC, READ, and SKCM (P < .05, HR > 1), but a favorable factor in BLCA, BRCA, CESC, HNSC, KIRP, LUAD, sarcoma (SARC), thymoma (THYM), and uveal melanoma (UVM) (P < .05, HR < 1) (Fig. 7A). The gene discussed is PPM1M; the disease is colon adenocarcinoma.