A study measuring miRNA and the lncRNA transcriptional expression and secretion of EVs in an HCC cell line (HepG2) and a non-tumor hepatocyte cell line indicated that HepG2-derived EVs contained lower levels of H19 and different miRNAs compared to the non-tumor cell line, indicating possible different modes of regulation between normal and cancer cells [78]. The gene discussed is H19; the disease is neoplasm.