That is to say, after removing the influence of rs1385492, we found that there was a correlation between OPG and AMI/CHD (AMI: weighted median OR = 0.818;95% CI = 0.724–0.950; p = 0.001; 6SNPs;CHD:weighted median OR = 0.842; 95% CI = 0.755–0.938; p = 1.893×10−3; 6SNPs; Table 3; Figure 8). This evidence concerns the gene TNFRSF11B and coronary artery disorder.