BDNF and Cerebral ischemia: In a study of middle-aged female rats, treated with WBV from 1 to 30 days after mid-cerebral ischemia-reperfusion, decreased inflammasome activation (caspase-1 and IL1-beta) and increased brain-derived neurotrophic factor (BDNF) expression were observed, concomitant with infarct reduction (Raval et al., 2018).