Incubation of PBMC with EVs from U87 human GBM cell line results in dramatic increase in expression of markers CD14, CD16, CD32, CD45, CD163; and increased secretion of IL-6, MCP-1 and VEGF (Azambuja et al., 2020; Xu et al., 2021a). The gene discussed is CD14; the disease is glioblastoma.