Nonetheless, statistical significance was reached only for the increased percentage of CD158a positive immature cells, and decreased percentages of CD159a immature, mature and hypermature NK cells on one side, and for the increased levels of expression of CD158e1 and CD159a on mature and hypermature NK cells for the AML group on the other side. The gene discussed is KIR2DL1; the disease is acute myeloid leukemia.