CD4 and influenza: In this study, mice immunized with the TCM-adjuvanted influenza vaccine exhibited significantly higher expression of CD11c+MHC II+, CD11c+CD80+, CD11c+CD86+, and CD3+CD4+, and have a higher proliferation index of T and B cell, compared with mice receiving vaccination alone, indicating that TCM may promote the maturation of DCs and activate innate and adaptive immunity in the immune response of the influenza vaccine.