The analysis of variance (ANOVA) of the FBG observation after the first week indicated that HSP augmentation was superior to metformin administration (Supplementary Table 1, P = 0.0098), and Duncan's multiple range test showed that HSP at a concentration of 2.5% or 5.0% did not have a significant difference in controlling the FBG level of T2D model rats. Here, HSP90B2P is linked to type 2 diabetes mellitus.