Regarding diabetes-specific risk factors, 94% (n=94) had a diabetes duration longer than five years; HbA1c greater than 7% in 70% (n=70); 62% (n=62) had microvascular complications; 83% (n=83) were on insulin, 2% (n=2) on canagliflozin and 1% (n=1) on pioglitazone (Table 1). The gene discussed is INS; the disease is diabetes mellitus.