PTOV1 and malignant colon neoplasm: We also examined the effect of the PTOV1-AS2/miR-145-5p/FSCN1 axis on the biological functions of colon cancer cells using a colon cancer cell line model with silenced expression PTOV1-AS2 and simultaneous silencing of miR-145-5p or upregulated FSCN1 expression.