We also explored the interaction between lncRNA PTOV1-AS2 and miR-145-5p and its target gene FSCN1 in order to determine the prospective application of the lncRNA PTOV1-AS2/miR-145-5p/FSCN1 axis in the diagnosis and prognosis of colon cancer. This evidence concerns the gene PTOV1 and malignant colon neoplasm.