A recent multicenter retrospective study in northern Japan found that, compared with non-AP, AP patients have lower BMI (19.4 ± 4.0 vs. 21.4 ± 4.6), C-reactive protein (9.4 ± 8.5 vs. 11.5 ± 9.8 mg/dL), and serum albumin (3.1 ± 0.6 vs. 3.2 ± 0.6) g/dL); higher rates of cerebrovascular disease, dementia and neuromuscular disease complications; and higher mortality rates (Suzuki et al., 2021). The gene discussed is CRP; the disease is alkaline phosphatase measurement.