As shown in Table 2, m6A regulators, including METTL3, FTO, and IGF2BP2, function as tumor promoters through the C-myc pathway in an m6A dependent manner, promoting growth, invasion, migration, and progression in various tumors such as lung cancer (65), bladder cancer (66), oral squamous cell carcinoma (OSCC) (67), CRC (68), prostate carcinoma (PCa) (69), and Gastric Cancer (70). This evidence concerns the gene METTL3 and colorectal carcinoma.