Another mAb targeting KIR2DL1/2/3, IPH2102, has failed to exert impressive clinical effects in patients with multiple myeloma (MM) as monotherapy, but when combined with lenalidomide in a dual immunotherapy for MM patients, it has been reported to achieve a median progression-free survival of 24 months, suggesting the promise of combination therapy (95). The gene discussed is KIR2DL1; the disease is Miyoshi myopathy.