The leukemia microenvironment contained significantly more PD-L1 (spleen: p<0.01; BM: p<0.01) and PD-L2 (spleen: p<0.001; BM: p<0.01) expressing LAMs in vehicle-treated mice compared to MRX2843-treated mice (Figures 2A, B; Table 1; Supplemental Figure 2A). Here, CD274 is linked to leukemia.